Somewhere in the handbook, after you've read the first hundred pages covering, 'elf n' safety, it should advise you to run the air/con for at least half an hour a week all year round, it stops the joints from drying out and leaking.
My previous car was a CRV, which I'd bought new 20 years before. When I sold it last March, everything still worked including the air/con which had never needed re-gassing, as I'd done what it said in the handbook.