You need to check thread length, heat range and spark position on the Iridium originals and the non-iridium and see if any differences. NGK spec explanation sheet attached as PDF
Iridium plugs are easier on the coil packs than normal plugs as the finer electrodes need less voltage to make a spark. Other than that if other spec like heat range and spark position are OK go for it.
The 'R' in NGK number means resistor, there is a 5,000 ohm resistor built into plug ( used to be built into plug caps ) for interference suppression - fitting a non resistor plug in place of a resistor one can cause problems, and the other way around as if there is already a 5Kohm in the system and you put in a plug with another 5K built in the spark will be weak.